Reference:ICH ICH E9 Guideline 1998 2.3

Document Information

Document information
Reference	ICH ICH E9 Guideline 1998
Validity area	ICH
Scope(s)	HM
Document name	ICH E9 Guideline
Version / Revision	1998
Status	Current
Document type	International guideline
Language(s)	EN
Description	STATISTICAL PRINCIPLES FOR CLINICAL TRIALS E9
Official source	Official link
Restricted access	No
Submitted by	Florian Adragna
Contributors

Reference Details

Scope	HM
Document part	2.3
Language	EN
Original entry by	Florian Adragna
Contributors
Tags (EN)
Tags (original language)
Tags (FR)
Comment	Design techniques to avoid bias: randomisation and blinding

Text

2.3 Design Techniques to Avoid Bias The most important design techniques for avoiding bias in clinical trials are blinding and randomisation, and these should be normal features of most controlled clinical trials intended to be included in a marketing application. Most such trials follow a double-blind approach [...]